Your hardware settings have changed, please reboot your computer for these changes to take effect.

100% Working!!! Fix easily...Your hardware settings have changed, please reboot your computer for these changes to take effect. This error is usually coming on the computer which has AMD graphics card.

You can easily disable this pop-up error message by just disabling AMD external event utility.

I have just reformated one laptop with an AMD graphics card. But just after installing the original AMD display driver from the manufacturer's website, the error message begins. "Your hardware settings have changed, please reboot your computer for these changes to take effect". I was totally confused with this annoying popup saying to reboot your computer. Then I realized that the problem might be related to display driver. I have just disabled the AMD external event utility and the problem solved.

There may be other reasons too to occur this kind of system settings change reboot errors. But on this system with AMD Radeon display driver, this problem can be solved in this method.